A quantum leap for biology

The University of Queensland has launched a $45 million research initiative to position Australia as a global leader in quantum biotechnology, and tackle some of the world’s biggest challenges.

The ARC Centre of Excellence in Quantum Biotechnology (QUBIC) brings together quantum technologies with life sciences, paving the way for advancements in health, energy and agriculture.

Led by Professor Warwick Bowen from UQ’s School of Mathematics and Physics, QUBIC is a multi-disciplinary collaboration involving 5 Australian universities, industry and government partners.

“The aim is to revolutionise the technology available to biosciences and biotechnology,” Professor Bowen said.

“By applying quantum computing and sensing to cells, molecules and even the brain, QUBIC’s research will transform our understanding of biology, from how enzymes trigger reactions to how viruses invade cells and how our brains function.”

QUBIC Deputy Director, Professor Halina Rubinsztein-Dunlop, said the centre has the potential for real impact.

“We are leading global quantum biotechnology innovation and creating the quantum workforce of the future – a pipeline of qualified people to take advantage of this emerging field in biotechnology,” Professor Rubinsztein-Dunlop said.

By 2045, this field is expected to generate 50,000 jobs and contribute $9 billion to Australia’s economy.

QUIBIC Director of Technology, Distinguished Professor Dayong Jin said the research will bridge quantum and the biological sciences.

“By allowing us to observe biochemical pathways and detect early signs of disease, quantum biotechnology will transform our understanding of subcellular compartments,” Professor Jin said.

“This innovation will significantly boost Australia’s capabilities in biotechnology, diagnostics and manufacturing, making us more competitive on the global stage.”

Professor Bowen said QUBIC’s research was well underway with a team of leading university researchers, industry and government partners and experts including CSIRO.

“I’m thrilled to be part of this diverse, multidisciplinary team, pioneering the field of quantum biotechnology and delivering real-world outcomes.”

Media: QUBIC Communications, connect.qubic@uq.edu.au +61 404 618 722

Image: L-R Adjunct Professor Christine Williams, Dr Alan Finkel AC FAA FTSE, The Honourable Gabrielle Upton, Dr Richard Johnson, Professor Warwick Bowen, Professor Halina Rubinsztein-Dunlop, Professor Deborah Terry AO, Ms Rachael Birks

Diamonds are the cornerstone of innovative quantum tools to measure brain activity

Since the 1970’s the gold standard technique for measuring the activity of individual neurons has been patch clamp, which uses an electrode to record the activity of a single neuron.

However, this measurement destroys the cell, limiting the timeframe of experiments to minutes and can only measure the activity of one neuron at a time.

We are developing novel techniques harnessing the power of quantum technologies to provide new ways to measure brain activity from individual neurons, or whole networks of neurons.

We culture the neurons on lab-grown diamonds to visualise neuronal activity. Through imaging neuronal activity, rather than using electrodes as in patch clamp, the measurements can be taken over long periods of time.

In the future this will allow us to visualise activity across the whole brain and understand how individual neurons connect with each other to coordinate the intricate functions of the brain 

Image: Neurons cultured on a diamond, Ooi Lab, University of Wollongong